| since 2004 | Member of APOPIS (Integrated Research Project on “Abnormal Protein Aggregation in Neurodegeneration” - funded by the European Union, 6th Research Framework - 39 European research institutions |
| since 2003 | Chairman of the German Parkinson Study Group (GPS) of the Competence Network on Parkinson's Disease |
| 2001 - 2004 | Coordinator of the European network of research, diagnosis and therapy in Parkinson’s disease (EuroPa), supported by the European Community, coordinated by the Dep. Neurology, University Marburg (11 European countries participating) |
| 2001 - 2002 | Coordinator of the national Remote-Data-Entry-internet based patient registry ‘restless legs syndrome’, supported by the German ministry (BMBF), coordinated by the Dep. Neurology, University Marburg (7 Universities participating) |
| since 2000 | Member, board of directors of the coordination centre for clinical studies (KKS), Marburg, supported by the German ministry of education and research (BMBF) |
| 1999 - 2007 | Coordinator of the German medical competence Network „Parkinson Syndrome“, supported by the German ministry of education and research (22 universities and 22 specialised Parkinson clinics participating) |
| 1999 - 2000 | Initiator of the Hertie-Institute for clinical brain research, University Tübingen |
| 1994 | Co-founder - together with Prof. Dr. P. Mehrain - of the "German Brain Bank for neurodegenerative disorders", Ludwig-Maximilians-University München |
| 1990 - 1996 | Coordinator of the Munich research program "Morbus Parkinson and other basal ganglia disorders", supported by the German ministry of education and research |
Organisation of study groups and meetings
Organizer and member of the organisation committees of more than 50 national and international congresses, conferences, meetings and study program meetings
Experience with clinical trials
| since 1996 | Principal Investigator for more than 30 clinical trials Investigator for more than 60 clinical trials Experience in planing and performing Investigator Initiated Trials Experience in performing national and international Multicenter Trials due to ICH-GCP for patients with Parkinson´s Disease, patients with Atypical Parkinsonian Syndromes, patients with Parkinson´s Disease Dementia and patients with Restless Legs Syndrome |
Main research
Parkinson’s disease and atypical Parkinson syndrome: prodromal stages, diagnosis, imaging, disease modification, pharmacotherapy, functional neurosurgery, stemcell research, animal models for neurodegenerative diseases; Wilson’s disease; neurological sleep disorders: REM-sleep-behaviour-disorders, narcolepsy, restless legs syndrome, Alzheimer’s disease, Lewy-body dementia: diagnosis, pharmacotherapy